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研究事務處

Cognitive and Neuroimaging Studies of the Schizophrenia Spectrum

Topic:	Cognitive and Neuroimaging Studies of the Schizophrenia Spectrum
Date & Time:	12 June 2017 (Monday) 3 PM
Venue:	Lecture Theatre 1, 2/F, King’s Park Campus, Tung Wah College
Speakers:	Professor Ulrich Ettinger, Department of Psychology, University of Bonn, Germany
Language:	English
Registration:	Now open for free registration at https://goo.gl/forms/GNouPX3LLG8d7nQw1

All HK registered/enrolled nurses will be awarded 1 CNE point for attending the Research Seminar

Attached please find the leaflet and presentation abstract for your information.

TWC- Professor Ulrich Ettinger Research seminar(12 Jun 2017,MON)-page-001

Presentation Abstract:

The phenomenology of schizotypy suggests that this constellation of traits represents a subclinical expression of schizophrenia. Neuropsychological and brain imaging studies are crucial to further bolster this claim. In this talk, I will present new results on cognitive, neuroimaging and pharmacological studies of schizotypy that aim to identify both similarities and dissimilarities between schizotypy and schizophrenia. Genetic risk populations are additionally considered to further demarcate the boundaries between these different schizophrenia spectrum populations. Higher-level, as well as basic cognitive and motor functions, are studied in the laboratory in relation to schizotypy, using both extreme groups and continuous sampling methods in healthy volunteers. Schizophrenia patients and clinically unaffected first-degree relatives of patients are studied for comparison. A replicable impairment in response inhibition is observed in high schizotypy. This impairment and its neural correlates overlap in part with the deficits seen in schizophrenia. The profile of impairment diverges, however, from that seen in relatives, who are mostly characterised by difficulties in complex sensorimotor transformations on oculomotor tasks. Evidence from pharmacological challenge studies points to selective tolerance of antipsychotic compounds in high, but not low, schizotypal individuals. The results from these recent studies support the conclusion that schizotypal traits in the general population represent a phenotype that bears resemblance with schizophrenia not only at the level of phenomenology but also at the levels of brain function, cognition and neurotransmitter system function.

Should you have any enquiries, please contact Ms. Candy Hui at 3190 6686 or email to us at [email protected].

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