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About TWC

Undergraduate and Sub-degree Programmes

Postgraduate Programme

Programmes

Postgraduate Programme

Doctor of Philosophy in Nursing (PhD(N))
Bachelor’s Degree Programmes

Bachelor of Education (Honours) in Early Childhood Education

Bachelor of Health Information and Services Management (Honours)

Bachelor of Health Science (Honours) in Nursing

Bachelor of Management (Honours) in Social and Business Sustainability

Bachelor of Science (Honours) in Applied Gerontology

Bachelor of Science (Honours) in Biomedical Science

Bachelor of Science (Honours) in Forensic Biomedical Science

Bachelor of Science (Honours) in Medical Imaging

Bachelor of Science (Honours) in Medical Laboratory Science

Certificate Programme

Certificate in Endoscopy Care

Certificate in Elderly Community Care and Support (Senior Secondary Applied Learning)
Mainland Admission

内地生入学计划

Academic Units

Administration Units

Teaching & Learning

Research & Impact

Partnership & Engagement

News & Events

School of Medical and Health Sciences

Dr. Marco Shing Yau TAM

Assistant Professor (Radiation Therapy)

Office: 2/F, School of Medical and Health Science, Nelson Court, 45 Waterloo Road, Mong Kok, Kowloon, Hong Kong

Tel : (852) 34686624

Fax: (852) 2783 8635

Email : marcotam@twc.edu.hk

Biography

Dr. Tam is an Assistant Professor in the School of Medical and Health Sciences at Tung Wah College. Before joining Tung Wah College in 2023, he was a Research Assistant Professor in the Department of Health Technology and Informatics at The Hong Kong Polytechnic University and a Visiting Scholar in the Department of Micro Engineering at Kyoto University, Japan. He has supervised undergraduate and secondary school students in research mentoring programmes and honours projects.

Dr. Tam’s research focuses on colorectal cancer prognosis and survivorship, with particular emphasis on the tumour microenvironment, radiomics and personalized radiotherapy. His work spans in vitro, in vivo and clinical studies and increasingly integrates multi‑omics and machine learning for risk stratification and toxicity prediction. To date, he has published more than 35 peer‑reviewed journal papers and conference abstracts, including 17 as first or corresponding author, with over 2900 citations and an h‑index of 15. He serves as editorial board member, guest editor and reviewer for several international peer‑reviewed journals.

Academic Qualifications

PhD (2019), The Hong Kong Polytechnic University
BSc (Hon) in Radiography (Radiation therapy stream, First Class Honors) (2014), The Hong Kong Polytechnic University
Registered Radiographer Part II Category T, Hong Kong Radiographers Board
Fellow (FIBMS), Institute of Biomedical Science (UK)
Member (MRSB), Royal Society of Biology (UK)

Author Identifications

ORCID: 0000-0002-5899-1041
Scopus: 57193488434 (Citation: 2810, H-index: 14)Google Scholar: https://scholar.google.com/citations?user=vy9lppMAAAAJ&hl=zh-TW (H-index: 16, i10-Index: 21; 17 first/corresponding-author papers with 933 citations, including three first-author papers each cited over 100 times)

Honours and Awards (Selected)
2025 Shape Your Skills (Abstract Scholarship), ECR 2026, European Society of Radiology (ESR)

2024 Early Career Researcher Award 2023/24, TWC
2023 Faculty Team Teaching Award (Co-PL), FHSS, HKPolyU
Departmental Team Teaching Award (Co-PL), Dept of HTI, HKPolyU
Co-innovation Award (Team member), Health Future Challenge 2023, HKPolyU
2021 Fellowship Award, The Japan Society for the Promotion of Science (JSPS)
Invitational Fellowship for Research in Japan (Short-term)
2019 Li Po Chun Charitable Trust Fund Scholarship
2014 First Class Honours in BSc (Hons) in Radiography (Radiation Therapy)
2014 Dean’s Honours List, Faculty of Health and Social Sciences, HKPolyU
2011-2014 The Hong Kong Polytechnic University Entry Scholarship (Academic)

Teaching Areas

Radiobiology
Radiation Therapy
Radiation Protection
Contemporary Cancer Therapy
Honors Year Project

Research Interests

Radiomics
Colorectal cancer
Tumour microenvironment (autophagy, epithelial–mesenchymal transition, hypoxia, metastasis, stemness maintenance)
Personalized radiotherapy
Radiation protection

Funded Projects (Selected)

2021.1-2023.6	Investigation on the psychosocial needs of post-radiotherapy rectal cancer survivors and their direct caregivers in Hong Kong Funded by Faculty Collaborative Research Scheme between Social Sciences and Health Sciences, FHSS, HKPolyU (HKD250,000, as Principal Investigator)
2021.2-2023.6	Development of a new undergraduate subject in interdisciplinary cancer research Funded by Strategic Plan Initiatives to Expand Research Elements in the Undergraduate Curriculum 2020-22, HKPolyU (HKD400,000, as Co-Project Leader)
2021.4-2023.6	Deciphering of the role of low oxygen level and JNK pathway in colorectal cancer progression and treatment response Funded by Start-up Fund for RAPs under the Strategic Hiring Scheme, HKPolyU (HKD250,000, as Principal Investigator)
2021.6-2021.8	Visualization of tumor microenvironment and epithelial-mesenchymal transition by on-chip vessels (オンチップ血管網による腫瘍微小環境と上皮間葉転換の可視化) Funded by Invitational Fellowships for Research in Japan, Japan Society for the Promotion of Science (JPY1,230,000, as Invited Fellow)
2021.7-2023.6	Evaluation of Treatment induced-ROS in TRAIL-mediated Pathway and Apoptosis in Colorectal Cancer Cells Funded by Undergraduate Research and Innovation Scheme (URIS), HKPolyU (HKD58,000, as Chief Supervisor)
2021.12-2022.11	Investigation of the role of JNK in chemoresistance in colorectal cancer (探索JNK在结直肠癌细胞化疗耐药中的作用) Funded by “百城百園”專項生命科學研究啟動基金, HKPolyU Shenzhen Research Institute (SZRI) (RMB225,000, as Principal Investigator)
2022.5-2023.6	Using augmented reality (AR) for visualizing scatter radiation in clinical environments for the teaching and learning of radiation protection Funded by Strategic Plan Initiatives to Enhance the Student Learning Experience through the Use of Interactive Pedagogies 2021-22, HKPolyU (HKD200,000, as Project Leader)
2024.4-2026.4	Building capacity to quantify radiation-induced urinary toxicities in rectal cancer patients: a pilot study Funded by Health and Medical Research Fund, Health Bureau (Project ID: 20211041, HKD499,993, as Principal Applicant)
2024.6-2026.5	Building an Interdisciplinary-based Smartphone Application to Manage the Radiation-induced Adverse Effects and Psychosocial Needs among Post-radiotherapy Rectal Cancer Patients and Caregivers: A Pilot Study Funded by College Research Grant, Tung Wah College (Project ID: CRG2023/03, HKD130,000, as Principal Investigator)
2024.6-2027.6	Evaluation of patient and organ doses in computed tomography and nuclear medicine protocols by Radiometrics Dose Management System Funded by Research Matching Grant, University Grants Committee (Project ID: 2023-02-75 RMGS230203, HKD700,000, as Principal Investigator)
2025.4-2027.4	Genomic Analysis of JNK and Hypoxia Signaling Pathways in Colorectal Cancer Prognosis Using Machine Learning Funded by College Research Grant, Tung Wah College (Project ID: CRG2024/02, HKD150,000, as Principal Investigator)

Publications (Selected)

1. Huang M, Chan MK, Cheng KL, Hui PY, Tam SY (Corresponding Author). Machine Learning-Based Prognosis Prediction in Glioblastoma Multiforme patients by Integrating Clinical Data with Multi-modal Radiomics. Diagnostics 2026;16:4:512. Doi: 10.3390/diagnostics16040512 (JCR Q1, IF 2024: 3.3)
2. Huang M, Law HKW, Tam SY (Corresponding Author). Radiomics-Driven Tumor Prognosis Prediction across Imaging Modalities: Advances in Sampling, Feature Selection, and Multi-Omics Integration. Cancers 2025;17:19:3121. Doi: 10.3390/cancers17193121 (JCR Q2, IF 2024: 4.4)
3. Tam SY (First and Corresponding Author), Man KH, Zhu S, Leung VWS, Mak SW, Tang WM, Law HKW. Evaluation of the Psychosocial Needs of Post-radiotherapy Rectal Cancer Survivors and their Caregivers in Hong Kong. J Med Imaging Radiat Sci 2025;56:6:102116. Doi: 10.1016/j.jmir.2025.102116 (JCR Q3, IF 2024: 2.0)
3. Huang M, Law HKW, Tam SY (Corresponding Author). Use of Radiomics in Characterizing Tumor Hypoxia. Int J Mol Sci 2025;26:14:6679. Doi: 10.3390/ijms26146679 (JCR Q1, IF 2024: 4.9)
4. Tam SY (First and Corresponding Author), Tang FH, Chan MY, Lai HC, Cheung S. Prognosis prediction in head and neck squamous cell carcinoma by radiomics and clinical information. Biomedicines 2024;12:8:1646. Doi: 10.3390/biomedicines12081646 (JCR Q1, IF 2024: 3.9)
5. Man KH, Law HKW, Tam SY (Corresponding Author). Psychosocial needs of post-radiotherapy cancer survivors and their direct caregivers – a systematic review. Front Oncol 2023;13:1246844. Doi: 10.3389/ fonc.2023.1246844 (IF 2022: 4.7)
6. Tam SY (First and Corresponding Author), Fung YY, Lau SY, Lam WN, Wong ETH. Scatter Radiation Distribution to Radiographers, Nearby Patients and Caretakers during Portable and Pediatric Radiography Examinations. Bioengineering 2023;10:7:779. Doi: 10.3390/bioengineering10070779 (IF 2022: 4.6)
7. Tam SY (First and Corresponding Author), Islam Khan MZ, Chen JY, Yip JHY, Yan HY, Tam TY, Law HKW. Proteomic profiling of chemotherapy responses in FOLFOX-resistant colorectal cancer cells. Int J Mol Sci 2023;24:12:9899. Doi: 10.3390/ijms24129899 (IF 2022: 5.6)
8. Tam SY (First and Corresponding Author), Islam Khan MZ, Yip JHY, Yan HY, Tam TY, Law HKW. Proteomic profiling of FOLFOX-resistant colorectal
cancer cells. J Clin Oncol 2023;41:16_suppl, e15588. Doi: 10.1200/JCO.2023.41.16_suppl.e15588 (IF 2022: 45.3)
9. Tam SY (First Author), Tam VCW, Law HKW, Khaw ML, Lee SWY. Rationale for Mass Masking in Controlling the COVID-19 Pandemic. Front Public Health 2021;9:665708. Doi: 10.3389/fpubh.2021.665708 (IF 2022: 5.2)
10. Tam SY (First and Corresponding Author), Law HKW. JNK in Tumor Microenvironment: Present Findings and Challenges in Clinical Translation. Cancers 2021;13:9:2196. Doi: 10.3390/cancers13092196 (IF 2022: 5.2)
11. Klionsky DJ, …, Tam SY et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 2021;1-382. Doi: 10.1080/15548627.2020.1797280 (IF 2022: 13.3)
12. Tam SY (First Author), Tam VCW, Ramkumar S, Khaw ML, Law HKW, Lee SWY. Review on the cellular mechanisms of low-level laser therapy use in oncology. Front Oncol 2020;10:1255. Doi: 10.3389/fonc.2020.01255 (IF 2022: 4.7)
13. Tam SY (First Author), Wu VWC, Law HKW. Hypoxia-induced Epithelial-Mesenchymal Transition in Cancers: HIF-1α and Beyond. Front Oncol 2020;10:486. Doi: 10.3389/fonc.2020.00486 (IF 2022: 4.7)
14. Tam SY (First Author), Wu VWC, Law HKW. JNK Pathway Mediates Low Oxygen Level Induced Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer Cells. Cancers 2020;12:1:224. Doi: 10.3390/cancers12010224 (IF 2022: 5.2)
15. Tam SY (First Author), Wu VWC, Law HKW. Dynamics of oxygen level-driven regulators in modulating autophagy in colorectal cancer cells. Biochem Biophys Res Commun 2019;517:2:193-200. Doi: 10.1016/j.bbrc.2019.07.043 (IF 2022: 3.1)
16. Tam SY (First Author), Wu VWC. A review on the special radiotherapy techniques of colorectal cancer. Front Oncol 2019;9:208. Doi: 10.3389/fonc.2019.00208 (IF 2022: 4.7)
17. Tam SY (First Author), Wu VWC, Law HKW. Influence of Autophagy on the Efficacy of Radiotherapy. Radiat Oncol 2017;12:57. Doi: 10.1186/s13014-017-0795-y (IF 2022: 3.6)

Community/ Professional Contributions (Selected)

2026-present	Guest Associate Editor, Frontiers in Oncology (Radiomics and Hypoxia Investigation for Personalizing Radiation Oncology)
2026-present	Guest Editor, Cancers (Modern Radiation Oncology: Predictions, Prognosis and Survival)
2025-present	Associate Editor, Frontiers in Neurology
2025-present	Member of European Society for Medical Oncology (ESMO)
2025-present	Review Editor, Frontiers in Oncology (Radiation Oncology section)
2024-2025	Member of Examination Board, TWC
2024-present	Editorial board member of Scientific Reports (Springer Nature, IF: 4.6)
2023-present	Member of Cancer Care research theme group, TWC
2023-present	Executive Committee Member, The Radiography Alumni Association of HKPolyU
2023-present	Topical Advisory Panel and Guest Editor for Gastroenterology Insights (MDPI)
2021-present	Reviewer board member of Frontiers in Bioscience-Landmark (IMR Press, IF: 3.1), Frontiers in Oncology (Frontiers, IF: 4.7)
2020-present	Member of Hong Kong Association of Radiation Therapists
2020-present	Member of The Hong Kong Radiographers’ Association
2020-present	Invited Reviewer for Bioengineered, Biology, Cancers, International Journal of Molecular Sciences, International Journal of Radiation Oncology, Journal of Cellular and Molecular Medicine and Journal of Selected Topics in Quantum Electronics
2020-2023	Departmental Health and Safety Officer, Dept of HTI, HKPolyU
2020-2023	Radiation Protection Officer, Dept of HTI, HKPolyU
2023-present	Executive Committee Member, The Radiography Alumni Association of HKPolyU
2023-present	Topical Advisory Panel and Guest Editor for Gastroenterology Insights (MDPI)
2021-present	Reviewer board member of Frontiers in Bioscience-Landmark (IMR Press, IF: 3.1), Frontiers in Oncology (Frontiers, IF: 4.7)
2020-present	Member of Hong Kong Association of Radiation Therapists
2020-present	Member of The Hong Kong Radiographers’ Association
2020-present	Invited Reviewer for Bioengineered, Biology, Cancers, International Journal of Molecular Sciences, International Journal of Radiation Oncology, Journal of Cellular and Molecular Medicine and Journal of Selected Topics in Quantum Electronics
2020-2023	Departmental Health and Safety Officer, Dept of HTI, HKPolyU
2020-2023	Radiation Protection Officer, Dept of HTI, HKPolyU