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News & EventsDr. Wilson Kin Chung LEUNG (梁健忠博士)Assistant Professor (助理教授)Office: 16/F, School of Nursing, Ma Kam Chan Memorial Building, 31 Wylie Road, Kowloon, Hong KongTelephone: 3190 6769Email: [email protected]BiographyDr. Wilson Leung obtained his Bachelor’s degree in Biochemistry at the Hong Kong University of Science and Technology, and continued his PhD studies in Anatomical and Cellular Pathology at the Chinese University of Hong Kong. In 2020, he has also obtained a Postgraduate Diploma in e-Health Informatics, with a research focus on mobile health apps use among older people. Meanwhile, he is an elderly fitness and outdoor fitness instructor recognized by the Physical Fitness Association of Hong Kong, China, and has also currently completed a Master degree in Sports Science.Besides basic science research, he is interested in multidisciplinary research areas mainly related to geriatric musculoskeletal conditions and movement patterns (physical activity and sedentary behavior) as well as chronic disease development (obesity, metabolic syndrome, type 2 diabetes, and liver cancer).Academic and Professional QualificationsBSc, PgDip, MSc, PhDAuthor IdentificationsORCID ID: 0000-0002-6196-4984EducationMaster of Science in Sports Science and Physical Activity, Faculty of Education, The Chinese University of Hong KongDoctor of Philosophy in Anatomical and Cellular Pathology, Faculty of Medicine, The Chinese University of Hong KongPostgraduate Diploma in e-Health Informatics, School of Professional and Continuing Education, The University of Hong KongBachelor of Science in Biochemistry, Faculty of Science, The Hong Kong University of Science and TechnologyHonours and AwardsDean’s List Academic Award, Dept. of Sports Science and Physical Education, CUHK (2023)Dean’s List Academic Award, Dept. of Biochemistry, HKUST (2007)Teaching AreasAnatomy and PhysiologyRecreational Activities and Exercises for All Ages and Older PeopleHealth InformaticsCapstone ProjectResearch InterestsPhysical activity and sedentary behavior in the elderlyBiomarkers for type 2 diabetes, central obesity, and metabolic syndromeMolecular pathogenesis of hepatocellular carcinomaFunded Projects (Selected)Exercise is Brain’s Fuel: A Systematic Review and Meta-Analysis of Brain-Derived Neurotrophic Factor-Associated Cognitive Functioning in Overweight and Obesity. College Research Grant 2022/2023 (Ref: CRG2022/04, peer-reviewed competitive grant), Tung Wah College (Principal Investigator) (Hong Kong, China) (2023-present)The beneficial role of Danshensu against doxorubicin-induced nephropathy via Nrf/HO-1 signaling axis. Funded by Collaborative Research Grants, Malmö University and The Hong Kong Polytechnic University Collaborative Research Grants Scheme (Co-investigator) (Hong Kong) (2017 - 2019)Roles of oxidative stress in Metabolic syndrome and its associated renal complications: a correlational study. Funded by Collaborative Research Grants, Griffith University and The Hong Kong Polytechnic University Collaborative Research Grants Scheme (Co-investigator) (Hong Kong) (2017 - 2019)Publications (Selected)Peer-reviewed journal articlesLeung, W. K. C., Yau, S. Y., Yang, Y., Kwok, A. W. L., Wong, E. M. L., Cheung, J. K. M., Shum, E. W. C., Lam, S. C.*, & Suen, L. K. P.* (2024). Effects of exercise interventions on brain-derived neurotrophic factor levels in overweight and obesity: A systematic review and meta-analysis. Journal of Exercise Science and Fitness, 22(4), 278-287. https://doi.org/10.1016/j.jesf.2024.04.001. [IF: 3.03, 2022]Leung, W. K. C., Yau, S. Y., Suen, L. K. P.*, & Lam, S. C.* (2023). Effects of exercise interventions on brain-derived neurotrophic factor expression in people with overweight and obesity: protocol for a systematic review and meta-analysis. BMJ Open, 13(10), Article e076118. http://doi.org/10.1136/bmjopen-2023-076118. [IF: 2.9, 2022]Leung, K. W., Yang, Y. J., Hui, S. S., & Woo, J. (2021). Mind-Body Health Benefits of Traditional Chinese Qigong on Women: A Systematic Review of Randomized Controlled Trials. Evidence-based complementary and alternative medicine, 2021, 7443498. https://doi.org/10.1155/2021/7443498
(Review Article; Impact Factor: 2.650, Q2 in Complementary and Alternative Medicine)Leung, K. W., Sum, K. R., & Yang, Y. J. (2021). Patterns of Sedentary Behavior among Older Adults in Care Facilities: A Scoping Review. International journal of environmental research and public health, 18(5), 2710. https://doi.org/10.3390/ijerph18052710
(Review Article; Impact Factor: 4.614, Q1 in Public, Environmental and Occupational Health)Leung, W., Yu, A. P., Lai, C., & Siu, P. M. (2018). Association of Markers of Proinflammatory Phenotype and Beige Adipogenesis with Metabolic Syndrome in Chinese Centrally Obese Adults. Journal of diabetes research, 2018, 8956509. https://doi.org/10.1155/2018/8956509
(Original Research; Impact Factor: 4.061, Q2 in Endocrinology, Diabetes and Metabolism)Leung, W., Chu, K. L., & Lai, C. (2017). Sonographic evaluation of the immediate effects of eccentric heel drop exercise on Achilles tendon and gastrocnemius muscle stiffness using shear wave elastography. PeerJ, 5, e3592. https://doi.org/10.7717/peerj.3592
(Original Research; Impact Factor: 3.06, Q2 in Medicine (miscellaneous))Siu, S. P., Leung, W. K., Wan, P. S., Liu, E. K., & Lai, C. W. (2017). Association between sonographically measured mesenteric fat thickness and brachial artery flow-mediated dilation in Chinese young male adults. The Journal of international medical research, 45(6), 1930–1938. https://doi.org/10.1177/0300060516688407
(Original Research; Impact Factor: 1.573, Q3 in Medicine (miscellaneous))Leung, W. K., Gao, L., Siu, P. M., & Lai, C. W. (2016). Diabetic nephropathy and endothelial dysfunction: Current and future therapies, and emerging of vascular imaging for preclinical renal-kinetic study. Life sciences, 166, 121–130. https://doi.org/10.1016/j.lfs.2016.10.015
(Review Article; Impact Factor: 6.78, Q1 in Medicine (miscellaneous))Leung, W. K., He, M., Chan, A. W., Law, P. T., & Wong, N. (2015). Wnt/β-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion. Cancer letters, 362(1), 97–105. https://doi.org/10.1016/j.canlet.2015.03.023
(Original Research; Impact Factor: 9.756, Q1 in Cancer Research)Leung, W. K., Ching, A. K., Chan, A. W., Poon, T. C., Mian, H., Wong, A. S., To, K. F., & Wong, N. (2011). A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility. Oncogene, 30(44), 4464–4475. https://doi.org/10.1038/onc.2011.161
(Original Research; Impact Factor: 8.756, Q1 in Cancer Research)Leung, W. K., Ching, A. K., & Wong, N. (2011). Phosphorylation of Caldesmon by PFTAIRE1 kinase promotes actin binding and formation of stress fibers. Molecular and cellular biochemistry, 350(1-2), 201–206. https://doi.org/10.1007/s11010-010-0699-8
(Original Research; Impact Factor: 3.842, Q2 in Medicine (miscellaneous))Zhou, Q., Ching, A. K., Leung, W. K., Szeto, C. Y., Ho, S. M., Chan, P. K., Yuan, Y. F., Lai, P. B., Yeo, W., & Wong, N. (2011). Novel therapeutic potential in targeting microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma. International journal of oncology, 38(3), 721–731. https://doi.org/10.3892/ijo.2011.902
(Original Research; Impact Factor: 5.884, Q2 in Cancer Research)Book chapters梁健忠博士、鄧晞言、梅鈞堯、崔子臻 (2023)。“運動與退化性關節炎” 中國香港體適能總會健康體適能社區期刊 2023 年春年冬季季刊。https://sys.markethk.net/hkpfa/frontend/filedata/tbl_cms_doc/doc/590_1.pdf陳少鴻、黃嘉怡、吳詠怡、鄧鈺珍、莊秋淇、廖樂妍、冼嘉蕙、黎詠欣、梁健忠博士 (2022)。“氣功的魅力 · 女士的恩物 - 疫情下的居家必備「運動」良藥” 中國香港體適能總會健康體適能社區期刊 2022 年冬季季刊。http://www.hkpfa.org.hk/CustomPage/111/%E6%B0%A3%E5%8A%9F%E7%9A%84%E9%AD%85%E5%8A%9B_Winter%2002.pdf梁健忠教授、楊懌健教授 (2022)。“疫情下的長者運動訓練” 中國香港體適能總會健康體適能社區期刊 2022 年冬季季刊。http://www.hkpfa.org.hk/CustomPage/111/%E7%96%AB%E6%83%85%E4%B8%8B%E7%9A%84%E9%95%B7%E8%80%85%E9%81%8B%E5%8B%95%E8%A8%93%E7%B7%B4_winter%2001.pdf梁健忠博士、王春波醫生 (2022) 。“「打機」可延緩衰老 ? 運動遊戲 (Exergamimg) 在安老院舍的優勢” 中國香港體適能總會健康體適能社區期刊 2021 年冬季季刊。1-5. http://www.hkpfa.org.hk/CustomPage/97/%E5%81%A5%E5%BA%B7%E9%AB%94%E9%81%A9%E8%83%BD%E7%A4%BE%E5%8D%80%E6%9C%9F%E5%88%8A(Winter%202021).pdfLeung, W. K., Wong, N., & Liang, Q. (Eds.). (2011). Molecular Aspects of Hepatocellular Carcinoma (pp56-66). Australia: Bentham Science.Conference postersLeung, W. K. (2022). Effectiveness of exergaming for improving physical performance among older adults in care facilities: a systematic review. Poster/Abstract of 29th Annual Congress of Gerontology.Leung, W. K. & Yang, Y. (2021). Computer-Assisted Approach to Personalized Design of Exercise Programs for Older Adults in Care Facilities: Perspective from Care Professionals. Abstract of “The 12th Pan-Pacific Conference on Rehabilitation” Virtual Conference, 2021.Leung, W. K., Yang, Y., Cheung, W. H., & Yung, P. S. H. Promoting the Use of Hip Protectors in Care Facilities through a Structured Staff Training Programme. Abstract of “The 9th Frailty Fracture Network (FFN) Global Congress” Virtual Conference, 2021.Leung, W. K., He, M., Law, P. T., Ching, A. K., Chan, A. W., & Wong, N. MiR-183/96/182 cluster confers cell motile advantages in hepatocellular carcinoma. Abstract of “AACR 103rd Annual Meeting” Chicago, IL, 2012, 72(8), 4127. https://doi.org/10.1158/1538-7445.AM2012-4127.Leung, W. K., Ching, A. K., Chan, A. W., Poon, T. C., To, K. F., Wong, A. S., & Wong, N. A novel role of cdc-family gene PFTK1 in the control of liver cancer cell motility. Abstract of “AACR 101st Annual Meeting” Washington, DC, 2010, 70(8), 5297. https://doi.org/10.1158/1538-7445.AM10-5297.Zhou, Q, Ching, A. K., Leung, W. K., Szeto, C. Y., Ho, S. M., Holmes, C. C., Yuan, Y. F., Lai, P. B., Yeo, W., & Wong, N. Novel therapeutic potential in targeting the microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma. Poster/Abstract of “AACR 101st Annual Meeting” Washington, DC, 2010, 70(8), 4423. https://doi.org/10.1158/1538-7445.AM10-4423.Social mediaSkypost (晴報) (2020-10-19)
長者易跌斷髖骨 戴保護墊減風險Mingpao (明報) (2020-10-19)
長者「側跌」 髖骨折風險高5.5倍 練上肢肌肉撐地 戴護髖防身Community/ Professional Contributions (Selected)Elderly Fitness Instructor, Physical Fitness Association of Hong Kong, ChinaOutdoor Fitness Instructor, Physical Fitness Association of Hong Kong, ChinaFull member (Health Professional), Hong Kong Society of Medical InformaticsMember, Physical Fitness Association of Hong Kong, ChinaMember, The Asian Society for Adapted Physical Education and ExerciseMember, The Computer Ethics SocietyReview Editor, Frontiers in MedicineGuest Reviewer, Nursing OpenGuest Reviewer, The Journal of Exercise Science and FitnessSubject ExpertiseAnatomy and PhysiologyExercise Science
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