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Dr. TSANG Chi Ching
Senior Lecturer
Office: Room 1903, 19/F, School of Medical and Health Sciences, Ma Kam Chan Memorial Building, 31 Wylie Road, Homantin, Kowloon, Hong Kong
Tel : (852) 3468 6821
Fax: (852) 2783 8635
Dr. Chi Ching TSANG obtained his bachelor’s and doctoral degrees at The University of Hong Kong and he continued his post-doctoral training in the Department of Microbiology, Li Ka Shing Faculty of Medicine in his alma mater. He joined Tung Wah College in 2021 and is responsible to the teaching of the Medical Laboratory Science programme. His research focusses on infectious diseases, with an emphasis on medical mycology. In particular, he is interested in the emerging yeast pathogen Candida auris as well as the endemic but neglected thermally dimorphic fungal pathogenTalaromyces marneffei.
Academic Qualifications
PhD (Microbiology), The University of Hong Kong
BSc (Major in Microbiology and Major in Biochemistry, First Class Honours), The University of Hong Kong
Author Identifications
Professional Qualifications
Fellow, Institute of Biomedical Science (MIBMS), UK
Chartered Biologist, Royal Society of Biology (CBiol), UK
Member, Royal Society of Biology (MRSB), UK
Registered Medical Laboratory Technologist (Part II), Medical Laboratory Technologist Board, HK
Teaching Areas
Medical Laboratory Science
Microbiology, Virology & Infectious Diseases
Molecular Biology & Molecular Diagnostics
Human Physiology
Research Interests
Medical mycology
Emerging infectious diseases
Diagnostic microbiology
Antimicrobial resistance
Discovery & characterisation of novel pathogens
Funded Projects (Selected)
08/2023 – 08/2026 (Co-Applicant)
Circulating small RNA-based diagnostics for differentiation of Candida species in candidemia (22210432). Health and Medical Research Fund, Health Bureau. HK$1,200,000.
09/2022 – 08/2025 (Co-Investigator)
Mechanistic study of the modulation of antifungal susceptibility by Candida auris extracellular vesicles (15100322). General Research Fund, Research Grants Council. HK$1,180,218.
10/2021 – 11/2023 (Co-Applicant)
Novel small RNA-based diagnostics and therapeutics for SARS-CoV-2 (20190612). Health and Medical Research Fund, Food and Health Bureau. HK$1,149,160.
01/2021 – 12/2023 (Co-Applicant)
Development of a next-generation rapid diagnostic test for circulating enteroviruses in Hong Kong (CID-HKU-1). Commissioned Research on Control of Infectious Diseases (Phase IV), Food and Health Bureau. HK$1,800,000.
07/2020 – 06/2023 (Co-Investigator)
Elucidating the molecular pathogenesis and mechanism of hypervirulence in virus-infected Talaromyces marneffei (17117120). General Research Fund, Research Grants Council. HK$1,195,482.
04/2019 – 03/2022 (Co-Investigator)
Diagnosing fungal infections by artificial intelligence (MRP/026/18). Midstream Research Programme for Universities, Innovation and Technology Fund, Innovation and Technology Commission. HK$3,499,997.45.
01/2019 – 12/2021 (Co-Investigator)
Mechanistic study on the pathogenesis of Talaromyces marneffei conidial interaction with human bronchial epithelial cells (17104318). General Research Fund, Research Grants Council. HK$971,811.
Publications (Selected)
Chan W*, Chow FWN*, Tsang C-C*, Liu X, Yao W, Chan TTY, Siu GKH, Ho AYM, Luk KS, Lau SKP, Woo PCY. 2022. Induction of amphotericin B resistance in susceptible Candida auris by extracellular vesicles. Emerg Microbes Infect. 11:1900–1909.
Tsang C-C, Teng JLL, Lau SKP, Woo PCY. 2021. Rapid genomic diagnosis of fungal infections in the age of next-generation sequencing. J Fungi. 7:636.
Lau SKP*, He Z*, Tsang C-C*, Chan TTY, Luk HKH, Chan E, Li KSM, Fung J, Chow FWN, Tam AR, Chung TWH, Wong SCY, Que T-L, Fung KSC, Lung DC, Wu AKL, Hung IFN, Teng JLL, Wernery U, Hui S-W, Martelli P, Woo PCY. 2021. A sensitive and specific competitive enzyme-linked immunosorbent assay for serodiagnosis of COVID-19 in animals. Microorganisms. 9:1019.
Tsang C-C*, Chan K-F*, Chan W, Chan JFW, Au-Yeung RKH, Ngan AHY, Lin KPK, Lau SKP, Woo PCY. 2021. Hepatic phaeohyphomycosis due to a novel dematiaceous fungus, Pleurostoma hongkongense sp. nov., and importance of antifungal susceptibility testing. Emerg. Microbes Infect. 10:81–96.
Seelbinder B, Chen J, Brunke S, Vazquez-Uribe R, Santhaman R, Meyer AC, de Oliveira Lino FS, Chan K-F, Loos D, Imamovic L, Tsang C-C, Lam RPK, Sridhar S, Kang K, Hube B, Woo PCY, Sommer MOA, Panagiotou G. 2020. Antibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria. Microbiome. 8:133.
Tsang C-C*, Tang JYM*, Ye H, Xing F, Lo SKF, Xiao C, Han L, Wu AKL, Ngan AHY, Lay K-C, To Y-N, Sze- DTT, Chim OHY, Hui TWS, Leung CWH, Zhu T, Yao C, Tse BPH, Lau SKP, Woo PCY. 2020. Rare/cryptic Aspergillus species infections and importance of antifungal susceptibility testing. Mycoses. 63:1283–1298.
Chow FWN, Chan TTY, Tam AR, Zhao S, Yao W, Fung J, Cheng FKK, Lo GCS, Chu S, Aw-Yong KL, Tang JYM, Tsang C-C, Luk HKH, Wong ACP, Li KSM, Zhu L, He Z, Tam EWT, Chung TWH, Wong SCY, Que T-L, Fung KSC, Lung DC, Wu AKL, Hung IFN, Woo PCY, Lau SKP. 2020. A rapid, simple, inexpensive, and mobile colorimetric assay COVID-19-LAMP for mass on-site screening of COVID-19. Int. J. Mol. Sci. 21:5380.
Tsang C-C, Lau SKP, Woo PCY. 2019. Sixty years from Segretain's description: what have we learned and should learn about the basic mycology of Talaromyces marneffei? Mycopathologia. 184:721–729.
Tsang C-C, Tang JYM, Chan K-F, Lee C-Y, Chan JFW, Ngan AHY, Cheung M, Lau ECL, Li X, Ng RHY, Lai CKC, Fung KSC, Lau SKP, Woo PCY. 2019. Diversity of phenotypically nondermatophyte, non-Aspergillus filamentous fungi causing nail infections: importance of accurate identification and antifungal susceptibility testing. Emerg. Microbes. Infect. 8:531–541.
Wernery U*, Tsang C-C*, Hebel C, Damerau A, Kinne J, Cai J-P, Küspert H, Chan K-F, Joseph M, Xue S, Raghavan R, Tang JYM, Syriac G, Lau SKP, Jose S, Woo PCY. 2018. Serodiagnosis of aspergillosis in falcons (Falco spp.) by an Afmp1p-based enzyme-linked immunosorbent assay. Mycoses. 61:600–609.
Tsang C-C, Tang JYM, Lau SKP, Woo PCY. 2018. Taxonomy and evolution of Aspergillus, Penicillium and Talaromyces in the omics era – past, present and future. Comput. Struct. Biotechnol. J. 16:197–210.
Woo PCY, Lau SKP, Tsang C-C, Lau CCY, Wong P-C, Chow FWN, Fong JYH, Yuen K-Y. 2017. Coronavirus HKU15 in respiratory tract of pigs and first discovery of coronavirus quasispecies in 5′-untranslated region. Emerg. Microbes Infect. 6:e53.
Tsang C-C, Chan JFW, Pong W-M, Chen JHK, Ngan AHY, Cheung M, Lai CKC, Tsang DNC, Lau SKP, Woo PCY. 2016. Cutaneous hyalohyphomycosis due to Parengyodontium album gen. et comb. nov. Med. Mycol. 54:699–713.
Tsang C-C, Hui TWS, Lee K-C, Chen JHK, Ngan AHY, Tam EWT, Chan JFW, Wu AL, Cheung M, Tse BPH, Wu AKL, Lai CKC, Tsang DNC, Que T-L, Lam C-W, Yuen K-Y, Lau SKP, Woo PCY. 2016. Genetic diversity of Aspergillus species isolated from onychomycosis and Aspergillus hongkongensis sp. nov., with implications to antifungal susceptibility testing. Diagn. Microbiol. Infect. Dis. 84:125–134.
Tsang C-C, Chan JFW, Trendell-Smith NJ, Ngan AHY, Ling IWH, Lau SKP, Woo PCY. 2014. Subcutaneous phaeohyphomycosis in a patient with IgG4-related sclerosing disease caused by a novel ascomycete, Hongkongmyces pedis gen. et sp. nov.: first report of human infection associated with the family Lindgomycetaceae. Med. Mycol. 52:736–747.
Tsang C-C, Chan JFW, Ip PPC, Ngan AHY, Chen JHK, Lau SKP, Woo PCY. 2014. Subcutaneous phaeohyphomycotic nodule due to Phialemoniopsis hongkongensis sp. nov. J. Clin. Microbiol. 52:3280–3289.
*Co-first authorship (equal contribution)
Professional/Community Services (Selected)
07/2022 – Present
Associate Editor, Frontiers in Fungal Biology (Section: Fungal Genomics and Evolution)
05/2022 – Present
Co-Guest Editor, International Journal of Molecular Sciences (Special issue: Molecular Mechanisms of Fungal Pathogenesis and Antifungal Resistance)
03/2022 – Present
Topical Advisory Panel Member, International Journal of Molecular Sciences (Section: Molecular Microbiology)
10/2021 – 05/2023
Guest Associate Editor, Frontiers in Cellular and Infection Microbiology (Section: Fungal Pathogenesis)
08/2021 – Present
Guest Editor, Journal of Fungi (Special issue: Novel, Emerging and Neglected Fungal Pathogens for Humans and Animals)
Last updated on 16th June, 2023

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